TY - BOOK AU - Trivedi,Bijal P. TI - Breath from salt: a deadly genetic disease, a new era in science, and the patients and families who changed medicine forever SN - 9781948836371 PY - 2020/// CY - Dallas, TX PB - BenBella Books, Inc. KW - Cystic fibrosis KW - Treatment N1 - Includes bibliographical references (pages 511-540) and index; Prologue -- Hello, Joey, 1974 -- The treatment plan, 1974 -- Case 44 : Babies Hospital, New York City, 1935 -- A new disease, 1936-1937 -- An equal opportunity disease, 1938-1942 -- Christmas homecoming, 1974-1977 -- The sweat test, 1943-1960 -- A tribe of desperate parents, 1950-1955 -- Lessons from polio, 1955-1960 -- The registry, 1960-1966 -- The therapist, 1977 -- A disease in search of ideas, 1964-1980 -- The hitman cometh, 1979-1982 -- Salt and water, 1970-1981 -- Salty boy, 1981-1983 -- Birth of an advocate, 1984 -- Out of many, one, 1978-1984 -- The gene hunters, 1980-1984 -- Lucky number seven, 1984-1985 -- Kate, 1986 -- To screen or not to screen newborns, 1985 -- Michigan, 1985 -- Joey's long goodbye, 1986 -- Mad pursuit, 1987 -- The gene, 1989 -- Runny, like water, 1989-1994 -- Venture philanthropy : funding drug development, 1977-1999 -- The gene is the medicine, 1989-1991 -- Transforming the lungs, 1992-1993 -- First-in-human trials, 1993-1995 -- The Beall Curve, 1996-1997 -- The Joey Fund, 1989-1999 -- A network for developing therapeutic drugs, 1997-1998 -- Aurora, 1998-1999 -- The gates open, 1987-2000 -- A tale of four families : CF in the new millennium, 1999-2005 -- The takeover, 2001 -- Getting the band together, 2001-2003 -- Pay to play, 2002-2004 -- Molecular architects of Vertex West, 2004-2005 -- Rat to man, 2003-2004 -- A Christmas gift, 2004-2005 -- The lucky four, 2005-2007 -- The doorman launches the era of genetic medicine, 2007-2008 -- Disruption, Fall 2008 -- Tasting like average people, 2010-2012 -- Milestones to a cure, 2004-2015 -- Tackling the common mutation, 2004-2013 -- What mutation are you?, 2013-2014 -- The mother of all deals, 2014 -- Very personal clinical trials, 2012-2017 -- The triple, 2015-2017 -- The home stretch, 2018 -- The leftovers, 2015-2020 -- A new generation, 2017-2020 -- Epilogue: 2019-2020 N2 - "Science writer Bijal P. Trivedi gives a comprehensive look at cystic fibrosis, from its late 1930s discovery to the recent development of breakthrough treatments for 90% of patients, and the way treatments for the previously fatal disease are opening the door for curing other life-threatening conditions"-- ER -